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Friday, July 24, 2020 | History

4 edition of Hypothermia and cerebral ischemia found in the catalog.

Hypothermia and cerebral ischemia

Hypothermia and cerebral ischemia

mechanisms and clinical applications

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  • 39 Currently reading

Published by Humana Press in Totowa, N.J .
Written in English

    Subjects:
  • Cerebral ischemia -- Treatment.,
  • Brain damage -- Treatment.,
  • Brain -- Effect of cold on.,
  • Cold -- Therapeutic use.,
  • Brain Ischemia -- therapy.,
  • Hypothermia, Induced.,
  • Brain Injuries -- therapy.,
  • Cerebrovascular Accident -- therapy.

  • Edition Notes

    Includes bibliographical references and index.

    Statementedited by Carolina M. Maier and Gary K. Steinberg.
    ContributionsMaier, Carolina M., Steinberg, Gary K.
    Classifications
    LC ClassificationsRC388.5 .H97 2004
    The Physical Object
    Paginationx, 188 p. :
    Number of Pages188
    ID Numbers
    Open LibraryOL21801906M
    ISBN 10089603660X
    LC Control Number2003049949

    Mild Hypothermia Mitigates Post-Ischemic Neuronal Death Following Focal Cerebral Ischemia in Rat Brain: Immunohistochemical Study of Fas, Caspase-3 and TUNEL. Phanithi PB, Yoshida Y, Santana A, et. Mild hypothermia in the treatment of severe cerebral ischemia using cooling blankets is safe and does not lead to severe side effects. Mild hypothermia can help to control critically elevated ICP values in severe space-occupying stroke and may improve clinical outcome in these by:

      Hypothermia prevents the delayed decline in phosphocreatine and adenosine triphosphate, as well as the simultaneous increase in cerebral lactate concentration, seen 8–12 hours after hypoxia–ischemia in newborn piglets 29 However, it is not clear if preservation of energy metabolism in the delayed phase of injury is the primary mechanism Cited by:   This book, with a largely North American authorship and contributions from Germany and Japan, comprises 10 chapters that address experimental and clinical studies of mild hypothermia (reductions of 2 to 5° below normal brain temperature) in global and focal cerebral ischaemia, and in traumatic brain : A J Strong.

    By Carolina M. Maier, Gary K. Steinberg. A complete evaluate of the medical and scientific reports that experience resulted in the resurgence of curiosity in hypothermia as a neuroprotective approach within the remedy of stroke and stressful mind harm. issues of unique significance contain intraoperative and extensive care administration of hypothermia-treated sufferers, a /5(4). Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. This leads to poor oxygen supply or cerebral hypoxia and thus to the death of brain tissue or cerebral infarction / ischemic stroke. It is a sub-type of stroke along with subarachnoid hemorrhage and intracerebral hemorrhage.. Ischemia leads to alterations in brain metabolism Other names: Cerebral ischemia, Cerebrovascular ischemia.


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Hypothermia and cerebral ischemia Download PDF EPUB FB2

In Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications, leading investigators and pioneers from around the world take hypothermia from bench to bedside, comprehensively reviewing both the scientific and clinical studies that have led to its resurgence in the treatment of stroke.

Topics of special interest include Format: Hardcover. Read "Hypothermia and Cerebral Ischemia Mechanisms and Clinical Applications" by available from Rakuten Kobo. A comprehensive review of the scientific and clinical studies that have led to the resurgence of interest in hypothermia Brand: Humana Press.

In Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications, leading investigators and pioneers from around the world take hypothermia from bench to bedside, comprehensively reviewing both the scientific and clinical studies that have led to its resurgence in the treatment of stroke.

In Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications, leading investigators and pioneers from around the world take hypothermia from bench to bedside, comprehensively reviewing both the scientific and clinical studies that have led to its resurgence in the treatment of : Humana Press.

Clinical trials of hypothermia after cardiac arrest (global cerebral ischaemia) The experimental hypothermia studies in animal models of global cerebral ischaemia paved the way for several clinical trials conducted from late to (Table 1).Two medium sized phase III trials using surface cooling showed a similar degree of improvement in outcome (55% vs 39%) and Cited by:   Recently, Hong et al.

also showed that 48 h of mild hypothermia and 48 h of rewarming following acute ischemic stroke led to a lower incidence of hemorrhagic transformation, a better outcome measured by the modified Rankin Score, and a lesser degree of malignant cerebral edema.

This study had a much larger number of patients treated with 75 Cited by: Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications Softcover PDF DOwnload by Carolina M.

Maier (Editor), Gary K. Steinberg (Editor) A comprehensive review of the scientific and clinical studies that have led to the resurgence of interest in hypothermia as a neuroprotective strategy in the treatment of stroke and traumatic brain injury.

Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications. Maier and G. Steinberg (editors). Published by Humana Press, Totowa, New JerAuthor: N.M. Dearden.

Therapeutic hypothermia has been widely to be one of the most reliable neuroprotective therapies for several cerebral disorders and injuries (van der Worp et al.,Yenari and Han, ), including stroke, traumatic injury, global ischemia after cardiac arrest, and hypoxic-ischemic by: Lee "Hypothermia and Cerebral Ischemia Mechanisms and Clinical Applications" por disponible en Rakuten Kobo.

A comprehensive review of the scientific and clinical studies that have led to the resurgence of interest in hypothermia Brand: Humana Press. During hypothermia, oxygen is redistributed in the brain.

3 The cerebral metabolic rate, cerebral ICP, and neurotoxic sequelae of ischemia all decrease. Cerebral blood flow decreases with alpha-stat pH management of ABG but is maintained with pH-stat management (see D).

Huang F, Zhou L. Effect of mild hypothermia on the changes of cerebral blood flow, brain blood barrier and neuronal injuries following reperfusion of focal cerebral ischemia in rats.

Chin Med J (Engl). ISBN: X OCLC Number: Description: x, pages: illustrations ; 24 cm: Contents: Resurgence of hypothermia as a treatment for brain injury / Carolina M.

Maier and Gary K. Steinberg --The effects of hypothermia and hyperthermia in global cerebral ischemia / Myron D. Ginsberg and Ludmila Belayev --Mild. Hypothermia and Cerebral Ischemia: Mechanisms and Clinical Applications is intended to provide a comprehensive review of mild hypothermia, including the therapeutic potential of the methodology, limitations, and recent developments in both basic and clinical : Patricia H.

Petrozza. Get this from a library. Hypothermia and cerebral ischemia: mechanisms and clinical applications. [Carolina M Maier; Gary K Steinberg;] -- Hypothermia is one of the most effective neuroprotective therapies in experimental ischemia modes, and there is widespread interest in using it to treat stroke and traumatic brain injury (TBI).

Hypothermia and Cerebral Ischemia contains a plethora of up-to-date and important information on both basic and clinical research. It is worthwhile to recommend as a reference book for the student, scientist and physician who is interested in or involved in the study of mild hypothermia for the treatment of stroke and traumatic brain injury.

In this study we compared the efficacy of mild (35°C) and moderate (33°C) hypothermia alone and when combined with magnesium in a transient focal cerebral ischemia rat model.

Cerebral Ischemia and Post-Ischemic Treatment with Hypothermia. By Kym Campbell, Neville W. Knuckey and Bruno P. Meloni. Submitted: March 31st Reviewed: September 5th Published: March 2nd DOI: /Author: Kym Campbell, Neville W.

Knuckey, Bruno P. Meloni. Mechanisms affected by therapeutic hypothermia on the sub-acute stage of ischemic stroke. Ischemia activates both intrinsic and extrinsic pathway which will lead cell apoptosis. Cerebral ischemia can occur hours after DHCA, because CBF and CVR are deranged for several hours after temperatures return to normal.

Circulate cold blood minutes prior to rewarming (wash out metabolites) and consider selective cerebral perfusion if more than one hour of operative time is needed. A new rectal cooling device for therapeutic hypothermia (TH) therapy is designed and is applied in TH treatment of SD rats with ischemic-hypoxic brain damage.

Healthy adult SD rats (n = 45) were randomly assigned into four groups: the healthy control group (n = 5), the ischemia and hypoxia group (n = 10), the rectal TH cooling group (n = 18), and the ice blanket Cited by: 1.Clinical studies of induced hypothermia were conducted on humans based on successful cerebral ischemia animal models.

One of the first studies cooled 17 patients with stroke admitted within 12 hours from symptom onset (mean hours) for 6 hours.[ 43 ]Author: Edgar A. Samaniego.Neuroprotection in transient focal cerebral ischemia by combination drug therapy and mild hypothermia: comparison with customary therapeutic regimen.

Stroke, 6: [] Zausinger S, Scholler K, Plesnila N and Schmid-Elsaesser R. (). Combination drug therapy and mild hypothermia after transient focal cerebral ischemia in by: 5.